Posts Tagged ‘Restless Legs Syndrome’

Neurontin making a comeback? Kind of. GlaxoSmithKline is on the cusp of beginning a Phase III clinical trial of a “novel prodrug of gabapentin” (brand name: Neurontin) for the treatment of Restless Legs Syndrome and related sleep disturbances. While not every Fibromyalgia sufferer experiences RLS, it’s a common component of the syndrome.

Neurontin was highly prescribed seven to 10 years ago, off label. Then it came out the company marketing it had been lying to doctors about the drug’s off label uses. However, some doctors still prescribe the medicine for FM. In 2007, Pfizer released Lyrica, which is structurally related to Neurontin and is FDA-approved for the treatment of Fibromyalgia.


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